Enable WordPress MultiSite (SubDomain) With Nginx

Here is a good tutorial show you how to Enable WordPress MultiSite (SubDomain) With Nginx:

From WordPress 3.0, you have the ability to create a network of sites (Multisite). I will show you how to enable WordPress multisite (subdomain) features with nginx.

Wildcard sbdomain (DNS  + Nginx)

WordPress MultiSite feature works using wildcard subdomains, so you must also add a wildcard subdomain to your DNS records.